Epidemiology Research Group in Organ Transplantation

Interview: HIV and Transplantation: New Reasons for HOPE

Three years after the HOPE Act was signed by President Obama, and three months after the first HIV-positive to HIV-positive transplant in the US, Dr. Dorry Segev sits down with the Journal of the American Medical Association to discuss how far transplantation has come since the 1980s.

You can read the full interview here.

Lab Publications in AJT July 2016

Lab members Allan Massie, PhD and Sunjae Bae, KMD MPH had their papers published in the July issue of American Journal of Transplant.


A Risk Index for Living Donor Kidney Transplantation (pages 2077–2084)
A. B. Massie, J. Leanza, L. M. Fahmy, E. K. H. Chow, N. M. Desai, X. Luo, E. A. King, M. G. Bowring and D. L. Segev

This study proposes a risk index for living donor kidney transplant recipients, the LKDPI, which quantifies the risk of graft loss on the same scale as the KDPI. See editorial on page 1951 from Schold and Kaplan.


Changes in Discard Rate After the Introduction of the Kidney Donor Profile Index (KDPI) (pages 2202–2207)
S. Bae, A. B. Massie, X. Luo, S. Anjum, N. M. Desai and D. L. Segev

Providing the Kidney Donor Profile Index (KDPI) with deceased donor kidney offers is associated with increased discards of standard criteria donor kidneys with KDPI > 85, a subgroup where the old standard/extended criteria donor designation and the new KDPI scoring deliver opposing messages, suggesting the possibility of a labeling effect.

First HIV-positive to HIV-positive transplant in the US

After six years of starting the campaign in Washington D.C. and after three years of passing the HOPE Act, Johns Hopkins performs the first HIV-postive to HIV-positive transplant in the US. ERGOT’s own Dr. Dorry Segev took part in front-running for the change legislature that now allows the once illegal practice of donating HIV-positive organs. After identifying a problem that affected our patients, doing the research to better understand that problem, taking that to the Hill, and getting the bill passed, the first HIV-positive to HIV-positive transplant was performed by Johns Hopkins surgeons.

Photo credit to KRISTOPHER RADDER/U.S. Navy

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