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TransplantModels.com

Five of ERGOT’s developed transplant models can be found at transplantmodels.com.

Living Donor Risk Index (LKDPI)
This model predicts recipient risk of graft loss after living donor kidney transplantation based on donor characteristics, on the same scale as the KDPI.

ESRD Risk Tool for Kidney Donor Candidates
This model is intended for low-risk adults considering living kidney donation in the United States. It provides an estimate of 15-year and lifetime incidence of end-stage renal disease.

Infectious Risk Donors
When a patient with end stage renal disease (ESRD) on the waitlist for a kidney is offered an Infectious Risk Donor (IRD) kidney, they need to decide whether they will accept the IRD kidney and the associated infectious risk, or if they will decline it and continue to wait for the next available infectious-risk free kidney.

Transplant Candidacy for Patients 65+
This prediction model is intended for adults with ESRD on dialysis aged 65 and above; it provides the predicted probability of 3-year survival after kidney transplantation (KT). Patients with predicted 3-year post-KT survival in the top quintile are deemed “excellent” candidates.

Pediatric Transplant: Living or deceased donor first?
Most pediatric kidney transplant recipients live long enough to require retransplantation. The most beneficial timing for living donor transplantation in candidates with one living donor is not clear.

‘A Risk Index for Living Donor Kidney Transplantation’ in Top 10 of 2016 via AST, ASTS, and AJT

Congratulations to ERGOT’s Dr. Allan Massie, whose article A Risk Index for Living Donor Kidney Transplantation was named one of the Top 10 Accessed Articles in 2016 by AST, ASTS, and AJT!

Patterns of End-Stage Renal Disease Caused by Diabetes, Hypertension, and Glomerulonephritis in Live Kidney Donors

Completing the trilogy of papers published in the December issue of the American Journal of Transplantation that was dedicated to living donors, our lab looks for Patterns of End-Stage Renal Disease Caused by Diabetes, Hypertension, and Glomerulonephritis in Live Kidney Donors.

We looked at studies averaging less than 10 years of follow-up to better understand postdonation ESRD.

Smartphone App for Increasing Live Organ Donation

Following the American Journal of Transplantation’s theme of giving for their December article, they published our paper featuring our Smartphone App for Increasing Live Organ Donation.

The idea came from talking to waitlisted candidates for kidney transplant who reported substantial barriers to identifying a live donor. Our app aims to help ESRD patients eligible for transplantation create a dialog that tells their story and helps them reach out to friends and family through social medias.

That app, as of this blog post, is still in development.

Recipient Outcomes Following Transplantation of Allografts From Live Kidney Donors Who Subsequently Developed End-Stage Renal Disease

The American Journal of Transplantation dedicated their December issue to organ donors who gave the gift of life to over 13,066 people this year (as of 11/18/2016).

At ERGOT, we care about the health and well being of live donors. In Recipient Outcomes Following Transplantation of Allografts From Live Kidney Donors Who Subsequently Developed End-Stage Renal Disease, data shows that preexisting kidney disease might be one mechanism underlying live donor end-stage renal disease.

Lab Publications in AJT

Lab members Allan Massie, PhD and Sunjae Bae, KMD MPH had their papers published in the July issue of American Journal of Transplantation.

 

A Risk Index for Living Donor Kidney Transplantation (pages 2077–2084)
A. B. Massie, J. Leanza, L. M. Fahmy, E. K. H. Chow, N. M. Desai, X. Luo, E. A. King, M. G. Bowring and D. L. Segev

This study proposes a risk index for living donor kidney transplant recipients, the LKDPI, which quantifies the risk of graft loss on the same scale as the KDPI. See editorial on page 1951 from Schold and Kaplan.

 

Changes in Discard Rate After the Introduction of the Kidney Donor Profile Index (KDPI) (pages 2202–2207)
S. Bae, A. B. Massie, X. Luo, S. Anjum, N. M. Desai and D. L. Segev

Providing the Kidney Donor Profile Index (KDPI) with deceased donor kidney offers is associated with increased discards of standard criteria donor kidneys with KDPI > 85, a subgroup where the old standard/extended criteria donor designation and the new KDPI scoring deliver opposing messages, suggesting the possibility of a labeling effect.

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